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Association analysis of the LTA4H gene polymorphisms and pulmonary tuberculosis in 9115 subjects

Immunoregulatory eicosanoids have been implicated in protection from mycobacterial infection in cell and animal models. Recently, a study of the zebrafish embryo demonstrated that mutants of the lta4h gene, which encodes the leukotriene A4 hydrolase (LTA4H) enzyme of the eicosanoid pathway, have hyp...

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Autors principals: Curtis, James, Kopanitsa, Liliya, Stebbings, Emma, Speirs, Arran, Ignatyeva, Olga, Balabanova, Yanina, Nikolayevskyy, Vladyslav, Hoffner, Sven, Horstmann, Rolf, Drobniewski, Francis, Nejentsev, Sergey
Format: Artigo
Idioma:Inglês
Publicat: Churchill Livingstone 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3040790/
https://ncbi.nlm.nih.gov/pubmed/21112816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tube.2010.11.001
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