HmuY Haemophore and Gingipain Proteases Constitute a Unique Syntrophic System of Haem Acquisition by Porphyromonas gingivalis

Haem (iron protoporphyrin IX) is both an essential growth factor and virulence regulator for the periodontal pathogen Porphyromonas gingivalis, which acquires it mainly from haemoglobin via the sequential actions of the R- and K-specific gingipain proteases. The haem-binding lipoprotein haemophore H...

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Detalhes bibliográficos
Main Authors: Smalley, John W., Byrne, Dominic P., Birss, Andrew J., Wojtowicz, Halina, Sroka, Aneta, Potempa, Jan, Olczak, Teresa
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3040768/
https://ncbi.nlm.nih.gov/pubmed/21390208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017182
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