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Identification of filamin A as a BRCA1-interacting protein required for efficient DNA repair

The product of the breast and ovarian cancer susceptibility gene BRCA1 has been implicated in several aspects of the DNA damage response but its biochemical function in these processes has remained elusive. In order to probe BRCA1 function we conducted a yeast two-hybrid screening to identify intera...

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Autores principales: Velkova, Aneliya, Carvalho, Marcelo A., Johnson, Joseph O., Tavtigian, Sean V., Monteiro, Alvaro N.A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3040726/
https://ncbi.nlm.nih.gov/pubmed/20305393
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