Innate Sensing of HIV-Infected Cells

Cell-free HIV-1 virions are poor stimulators of type I interferon (IFN) production. We examined here how HIV-infected cells are recognized by plasmacytoid dendritic cells (pDCs) and by other cells. We show that infected lymphocytes are more potent inducers of IFN than virions. There are target cell-...

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Detalhes bibliográficos
Principais autores: Lepelley, Alice, Louis, Stéphanie, Sourisseau, Marion, Law, Helen K. W., Pothlichet, Julien, Schilte, Clémentine, Chaperot, Laurence, Plumas, Joël, Randall, Richard E., Si-Tahar, Mustapha, Mammano, Fabrizio, Albert, Matthew L., Schwartz, Olivier
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3040675/
https://ncbi.nlm.nih.gov/pubmed/21379343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1001284
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