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Tumor necrosis factor participates in the pathogenesis of acute immune complex alveolitis in the rat.

We have examined the role of intrapulmonary TNF in a rat model of acute immune complex-triggered alveolitis. Intratracheal instillation of IgG anti-bovine serum albumin (anti-BSA) followed by intravenous infusion of BSA results in acute alveolitis. Over the 4-h course of evolving lung injury, a 10-f...

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Publicado en:J Clin Invest
Autores principales: Warren, J S, Yabroff, K R, Remick, D G, Kunkel, S L, Chensue, S W, Kunkel, R G, Johnson, K J, Ward, P A
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 1989
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC304067/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2531759/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114374
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