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[SWI(+)], the Prion Formed by the Chromatin Remodeling Factor Swi1, Is Highly Sensitive to Alterations in Hsp70 Chaperone System Activity

The yeast prion [SWI(+)], formed of heritable amyloid aggregates of the Swi1 protein, results in a partial loss of function of the SWI/SNF chromatin-remodeling complex, required for the regulation of a diverse set of genes. Our genetic analysis revealed that [SWI(+)] propagation is highly dependent...

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Detalhes bibliográficos
Main Authors: Hines, Justin K., Li, Xiaomo, Du, Zhiqiang, Higurashi, Takashi, Li, Liming, Craig, Elizabeth A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3040656/
https://ncbi.nlm.nih.gov/pubmed/21379326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1001309
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