Mapping of the Disease Locus and Identification of ADAMTS10 As a Candidate Gene in a Canine Model of Primary Open Angle Glaucoma

Primary open angle glaucoma (POAG) is a leading cause of blindness worldwide, with elevated intraocular pressure as an important risk factor. Increased resistance to outflow of aqueous humor through the trabecular meshwork causes elevated intraocular pressure, but the specific mechanisms are unknown...

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Bibliographic Details
Main Authors: Kuchtey, John, Olson, Lana M., Rinkoski, Tommy, MacKay, Edward O., Iverson, T. M., Gelatt, Kirk N., Haines, Jonathan L., Kuchtey, Rachel W.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2011
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3040645/
https://ncbi.nlm.nih.gov/pubmed/21379321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1001306
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