Mapping of the Disease Locus and Identification of ADAMTS10 As a Candidate Gene in a Canine Model of Primary Open Angle Glaucoma

Primary open angle glaucoma (POAG) is a leading cause of blindness worldwide, with elevated intraocular pressure as an important risk factor. Increased resistance to outflow of aqueous humor through the trabecular meshwork causes elevated intraocular pressure, but the specific mechanisms are unknown...

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Main Authors: Kuchtey, John, Olson, Lana M., Rinkoski, Tommy, MacKay, Edward O., Iverson, T. M., Gelatt, Kirk N., Haines, Jonathan L., Kuchtey, Rachel W.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3040645/
https://ncbi.nlm.nih.gov/pubmed/21379321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1001306
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