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Defective dopamine-1 receptor adenylate cyclase coupling in the proximal convoluted tubule from the spontaneously hypertensive rat.

The natriuretic effect of DA-1 agonists is less in the spontaneously hypertensive rat (SHR) than its normotensive control, the Wistar-Kyoto rat (WKY). To determine a mechanism of the decreased effect of DA-1 agonists on sodium transport, DA-1 receptors in renal proximal convoluted tubule (PCT) were...

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Опубликовано в::J Clin Invest
Главные авторы: Kinoshita, S, Sidhu, A, Felder, R A
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Clinical Investigation 1989
Предметы:
Online-ссылка:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC304064/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2574187/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114371
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