Defective in vitro production of gamma-interferon and tumor necrosis factor-alpha by circulating T cells from patients with the hyper-immunoglobulin E syndrome.

Circulating T cells from four patients with the hyper-IgE syndrome were found to produce significantly lower concentrations of interferon-gamma (IFN-gamma) in response to stimulation with phytohemagglutinin (PHA) than did T cells from eight age-matched healthy controls, three patients with atopic de...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Del Prete, G, Tiri, A, Maggi, E, De Carli, M, Macchia, D, Parronchi, P, Rossi, M E, Pietrogrande, M C, Ricci, M, Romagnani, S
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1989
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC304061/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2531758/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114368
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