Induction of hypertrophy in cultured proximal tubule cells by extracellular NH4Cl.
Ammonia production increases in several models of renal hypertrophy in vivo. The present study was designed to determine whether ammonia can directly modulate the growth of renal cells in the absence of a change in extracellular acidity. In serum-free media NH4Cl (0-20 mM) caused JTC cells and a pri...
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| Udgivet i: | J Clin Invest |
|---|---|
| Principais autores: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Clinical Investigation
1989
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC304054/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2480366/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114361 |
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