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Mutational analysis of the role of GXXXG motif in the function of human organic anion transporter 1 (hOAT1)

Human organic anion transporter hOAT1 plays a critical role in the body disposition of environmental toxins and clinically important drugs including anti-HIV therapeutics, anti-tumor drugs, antibiotics, anti-hypertensives, and anti-inflammatories. hOAT1 has two GXXXG motifs in its transmembrane doma...

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Bibliographic Details
Main Authors: Duan, Peng, Wu, Jinwei, You, Guofeng
Format: Artigo
Language:Inglês
Published: e-Century Publishing Corporation 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3040413/
https://ncbi.nlm.nih.gov/pubmed/21340049
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