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A natural autoantibody is encoded by germline heavy and lambda light chain variable region genes without somatic mutation.
While nonmutated germline variable region (V) genes have been found to encode heavy or light chains of various human autoantibodies, the use of germline V genes by both chains of a given autoantibody has not been documented. Recently, we reported that the heavy chain V gene (designated Humha346) of...
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| Pubblicato in: | J Clin Invest |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Clinical Investigation
1989
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC304036/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2509520/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114347 |
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