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Mast Cell/IL-4 Control of Francisella tularensis Replication and Host Cell Death is Associated with Increased ATP Production and Phagosomal Acidification

Mast cells are now recognized as effective modulators of innate immunity. We recently reported that mast cells and secreted interleukin-4 (IL-4) effectively control intramacrophage replication of Francisella tularensis Live Vaccine Strain (LVS), and that mice deficient in mast cells or IL-4 receptor...

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Detalhes bibliográficos
Main Authors: Rodriguez, Annette R., Yu, Jieh-Juen, Murthy, Ashlesh K., Guentzel, M. Neal, Klose, Karl E., Forsthuber, Thomas G., Chambers, James P., Berton, Michael T., Arulanandam, Bernard. P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3040285/
https://ncbi.nlm.nih.gov/pubmed/20861832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2010.59
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