Fate mapping of interleukin 17-producing T cells in inflammatory responses

We describe a reporter mouse strain designed to fate-map cells that have activated IL-17A. Here we show that T(H)17 cells show distinct plasticity in different inflammatory settings. Chronic inflammatory conditions in EAE caused a switch to alternative cytokines in T(H)17 cells, whereas acute cutane...

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Bibliografiske detaljer
Main Authors: Hirota, K., Duarte, J.H., Veldhoen, M., Hornsby, E., Li, Y., Cua, D.J., Ahlfors, H., Wilhelm, C., Tolaini, M., Menzel, U., Garefalaki, A., Potocnik, A.J., Stockinger, B
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3040235/
https://ncbi.nlm.nih.gov/pubmed/21278737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.1993
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