Epidermal growth factor receptor defects in leprechaunism. A multiple growth factor-resistant syndrome.

Leprechaunism is a rare genetic disorder characterized by severe growth retardation and insulin resistance. Maximal epidermal growth factor (EGF) binding was reduced in fibroblasts from three unrelated patients with leprechaunism (Ark-1, Can-1, and Minn-1) compared with control (0.8-2.2%/mg protein...

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Pubblicato in:	J Clin Invest
Autori principali:	Reddy, S S, Kahn, C R
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 1989
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC304023/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2808704/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114334
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