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Understanding the effects of carbocyclic sugars constrained to north and south conformations on RNA nanodesign

Relatively new types of the modified nucleotides, namely carbocyclic sugars that are constrained to north or south (C2′ or C3′ exo) conformations, can be used for RNA nanoparticle design to control their structures and stability by rigidifying nucleotides and altering the helical properties of RNA d...

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Detalhes bibliográficos
Main Authors: Kim, Taejin, Barchi, Joseph J., Marquez, Victor E., Shapiro, Bruce A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3040123/
https://ncbi.nlm.nih.gov/pubmed/21159533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmgm.2010.11.007
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