Imatinib Mesylate in Advanced Dermatofibrosarcoma Protuberans: Pooled Analysis of Two Phase II Clinical Trials

PURPOSE: Dermatofibrosarcoma protuberans (DFSP) is a dermal sarcoma typically carrying a translocation between chromosomes 17 and 22 that generates functional platelet-derived growth factor B (PDGFB). PATIENTS AND METHODS: Two distinct phase II trials of imatinib (400 to 800 mg daily) in patients wi...

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Dades bibliogràfiques
Autors principals: Rutkowski, Piotr, Van Glabbeke, Martine, Rankin, Cathryn J., Ruka, Wlodzimierz, Rubin, Brian P., Debiec-Rychter, Maria, Lazar, Alexander, Gelderblom, Hans, Sciot, Raf, Lopez-Terrada, Dolores, Hohenberger, Peter, van Oosterom, Allan T., Schuetze, Scott M.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Clinical Oncology 2010
Matèries:
Original Reports
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3040044/
https://ncbi.nlm.nih.gov/pubmed/20194851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2009.25.7899
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