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Acylation of CD44 and Its Association with Lipid Rafts Are Required for Receptor and Hyaluronan Endocytosis

CD44 is a cell surface receptor for the extracellular matrix macromolecule hyaluronan. In addition, CD44 mediates the endocytosis of hyaluronan leading to its subsequent degradation within lysosomes. Using model systems of COS-7 and Flp-293 cells, we demonstrate that the association of CD44 with lip...

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Detalhes bibliográficos
Main Authors: Thankamony, Sai P., Knudson, Warren
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3039921/
https://ncbi.nlm.nih.gov/pubmed/16945930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M601530200
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