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Expansions of NK-like αβT cells with chronologic aging: Novel lymphocyte effectors that compensate for functional deficits of conventional NK cells and T cells

As the repertoire of αβT cell receptors (TCR) contracts with advancing age, there is an associated age-dependent accumulation of oligoclonal T cells expressing of a variety of receptors (NKR), normally expressed on natural killer (NK) cells. Evidences for differential regulation of expression of par...

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Detalhes bibliográficos
Main Authors: Vallejo, Abbe N., Mueller, Robert G., Hamel, David L., Way, Amanda, Dvergsten, Jeffrey A., Griffin, Patricia, Newman, Anne B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3039714/
https://ncbi.nlm.nih.gov/pubmed/20932941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.arr.2010.09.006
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