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T cell coinhibition in prostate cancer: new immune evasion pathways and emerging therapeutics

T cell-mediated adaptive immune response is controlled by both positive costimulation and negative coinhibition, generated mainly by the interaction between the B7 family and their receptor CD28 family. Coinhibition is exploited by prostate cancer as an immune evasion pathway. Overexpression of coin...

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Detalles Bibliográficos
Main Authors: Barach, Yael S, Lee, Jun Sik, Zang, Xingxing
Formato: Artigo
Idioma:Inglês
Publicado: 2011
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3039708/
https://ncbi.nlm.nih.gov/pubmed/20971039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmed.2010.09.006
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