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T cell coinhibition in prostate cancer: new immune evasion pathways and emerging therapeutics
T cell-mediated adaptive immune response is controlled by both positive costimulation and negative coinhibition, generated mainly by the interaction between the B7 family and their receptor CD28 family. Coinhibition is exploited by prostate cancer as an immune evasion pathway. Overexpression of coin...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3039708/ https://ncbi.nlm.nih.gov/pubmed/20971039 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmed.2010.09.006 |
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