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T cell coinhibition in prostate cancer: new immune evasion pathways and emerging therapeutics

T cell-mediated adaptive immune response is controlled by both positive costimulation and negative coinhibition, generated mainly by the interaction between the B7 family and their receptor CD28 family. Coinhibition is exploited by prostate cancer as an immune evasion pathway. Overexpression of coin...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Barach, Yael S, Lee, Jun Sik, Zang, Xingxing
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3039708/
https://ncbi.nlm.nih.gov/pubmed/20971039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmed.2010.09.006
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