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Multiple four-stranded conformations of human telomere sequence d(CCCTAA) in solution

By detailed NMR analysis of a human telomere repeating unit, d(CCCTAA), we have found that three distinct tetramers, each of which consists of four symmetric single-strands, slowly exchange in a slightly acidic solution. Our new finding is a novel i-motif topology (T-form) where T4 is intercalated b...

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Detalhes bibliográficos
Main Authors: Kanaori, Kenji, Shibayama, Naoko, Gohda, Keigo, Tajima, Kunihiko, Makino, Keisuke
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2001
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC30397/
https://ncbi.nlm.nih.gov/pubmed/11160907
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