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An In Vitro Model That Recapitulates the Epithelial to Mesenchymal Transition (EMT) in Human Breast Cancer

The epithelial to mesenchymal transition (EMT) is a developmental program in which epithelial cells down-regulate their cell-cell junctions, acquire spindle cell morphology and exhibit cellular motility. In human breast cancer, invasion into surrounding tissue is the first step in metastatic progres...

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Autors principals: Katz, Elad, Dubois-Marshall, Sylvie, Sims, Andrew H., Gautier, Philippe, Caldwell, Helen, Meehan, Richard R., Harrison, David J.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3039655/
https://ncbi.nlm.nih.gov/pubmed/21347235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017083
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