Improved Innate and Adaptive Immunostimulation by Genetically Modified HIV-1 Protein Expressing NYVAC Vectors

Attenuated poxviruses are safe and capable of expressing foreign antigens. Poxviruses are applied in veterinary vaccination and explored as candidate vaccines for humans. However, poxviruses express multiple genes encoding proteins that interfere with components of the innate and adaptive immune res...

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主要な著者: Quakkelaar, Esther D., Redeker, Anke, Haddad, Elias K., Harari, Alexandre, McCaughey, Stella Mayo, Duhen, Thomas, Filali-Mouhim, Abdelali, Goulet, Jean-Philippe, Loof, Nikki M., Ossendorp, Ferry, Perdiguero, Beatriz, Heinen, Paul, Gomez, Carmen E., Kibler, Karen V., Koelle, David M., Sékaly, Rafick P., Sallusto, Federica, Lanzavecchia, Antonio, Pantaleo, Giuseppe, Esteban, Mariano, Tartaglia, Jim, Jacobs, Bertram L., Melief, Cornelis J. M.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2011
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3039654/
https://ncbi.nlm.nih.gov/pubmed/21347234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016819
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