Isolation and characterization of a membrane protein from normal human erythrocytes that inhibits reactive lysis of the erythrocytes of paroxysmal nocturnal hemoglobinuria.

The observation that type III erythrocytes of paroxysmal nocturnal hemoglobinuria (PNH) are susceptible to hemolysis initiated by activated cobra venom factor complexes (CoFBb), whereas normal erythrocytes are resistant, implies that the PNH III cells are deficient in a membrane constituent that reg...

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Pubblicato in:	J Clin Invest
Autori principali:	Holguin, M H, Fredrick, L R, Bernshaw, N J, Wilcox, L A, Parker, C J
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 1989
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC303946/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2738160/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114172
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