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Paromomycin: uptake and resistance in Leishmania donovani

Paromomycin is currently in phase IV clinical trials against leishmaniasis. In the present work we elucidate the effect and mechanism of uptake of paromomycin in Leishmania donovani. The in vitro sensitivities of both promastigotes and amastigotes were determined to this aminoglycoside. Association...

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Detalhes bibliográficos
Main Authors: Jhingran, Anupam, Chawla, Bhavna, Saxena, Shailendra, Barrett, Michael Peter, Madhubala, Rentala
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3039421/
https://ncbi.nlm.nih.gov/pubmed/19146886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molbiopara.2008.12.007
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