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Characterization of concentration- and use-dependent effects of quinidine from conduction delay and declining conduction velocity in canine Purkinje fibers.

The dynamic response of squared conduction velocity, theta 2, to repetitive stimulation in canine Purkinje fibers with quinidine was studied using a double-microelectrode technique. With stimulation, a frequency-dependent monoexponential increase in conduction delay (CD) and a decline in theta 2 wer...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:J Clin Invest
Hauptverfasser: Packer, D L, Grant, A O, Strauss, H C, Starmer, C F
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 1989
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC303938/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2542382/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114124
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