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In obese Zucker rats, lipids accumulate in the heart despite normal mitochondrial content, morphology and long-chain fatty acid oxidation

We aimed to determine whether an increased rate of long-chain fatty acid (LCFA) transport and/or a reduction in mitochondrial oxidation contributes to lipid deposition in hearts, as lipid accumulation within cardiac muscle has been associated with heart failure. In hearts of lean and obese Zucker ra...

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Detalhes bibliográficos
Main Authors: Holloway, Graham P, Snook, Laelie A, Harris, Robert J, Glatz, Jan F C, Luiken, Joost J F P, Bonen, Arend
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3039267/
https://ncbi.nlm.nih.gov/pubmed/21041527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2010.198663
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