In obese Zucker rats, lipids accumulate in the heart despite normal mitochondrial content, morphology and long-chain fatty acid oxidation

We aimed to determine whether an increased rate of long-chain fatty acid (LCFA) transport and/or a reduction in mitochondrial oxidation contributes to lipid deposition in hearts, as lipid accumulation within cardiac muscle has been associated with heart failure. In hearts of lean and obese Zucker ra...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Holloway, Graham P, Snook, Laelie A, Harris, Robert J, Glatz, Jan F C, Luiken, Joost J F P, Bonen, Arend
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Blackwell Science Inc 2011
Pynciau:
Cardiovascular
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3039267/
https://ncbi.nlm.nih.gov/pubmed/21041527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2010.198663
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