Inhibition of Aberrant Androgen Receptor Induction of Prostate Specific Antigen Gene Expression, Cell Proliferation and Tumor Growth by 17α-Estradiol in Prostate Cancer

PURPOSE: Androgen independent prostate cancer growth and metastasis are a major cause of prostate cancer death. Aberrant androgen receptor activation due to androgen receptor mutation is an important mechanism of androgen independence. We determined the effectiveness and mechanism of 17α-estradiol (...

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Bibliographic Details
Main Authors: Qiao, Yaming, Wang, Lu, Cai, Li-Qun, Tan, Chen, Imperato-McGinley, Julianne, Zhu, Yuan-Shan
Format: Artigo
Language:Inglês
Published: 2011
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3039213/
https://ncbi.nlm.nih.gov/pubmed/21075385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.juro.2010.09.008
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