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Clonal analysis of childhood acute lymphoblastic leukemia with "cytogenetically independent" cell populations.

Acute lymphoblastic leukemia (ALL) is generally regarded as a clonal disease in which a single abnormal progenitor cell gives rise to neoplastic progeny. Five of 463 cases of childhood ALL with adequately banded leukemic cells were found to have two cytogenetically independent cell populations. In a...

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Sparad:
I publikationen:J Clin Invest
Huvudupphov: Pui, C H, Raskind, W H, Kitchingman, G R, Raimondi, S C, Behm, F G, Murphy, S B, Crist, W M, Fialkow, P J, Williams, D L
Materialtyp: Artigo
Språk:Inglês
Utgiven: American Society for Clinical Investigation 1989
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC303920/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2566623/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114106
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