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Metabotropic glutamate receptor blockade in nucleus accumbens shell shifts affective valence toward fear and displeasure
Glutamatergic inputs to the nucleus accumbens (NAc) modulate both appetitive and fearful motivation. Pathological disturbances of glutamate signaling in NAc have been suggested to contribute to motivation disorders, ranging from excessive desire in drug addiction to paranoia in schizophrenia. Metabo...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3039038/ https://ncbi.nlm.nih.gov/pubmed/21198990 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1460-9568.2010.07553.x |
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