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Antisense-mediated decrease in DNA ligase III expression results in reduced mitochondrial DNA integrity

The human DNA ligase III gene encodes both nuclear and mitochondrial proteins. Abundant evidence supports the conclusion that the nuclear DNA ligase III protein plays an essential role in both base excision repair and homologous recombination. However, the role of DNA ligase III protein in mitochond...

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Autors principals: Lakshmipathy, Uma, Campbell, Colin
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC30390/
https://ncbi.nlm.nih.gov/pubmed/11160888
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