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Human colony-forming units-erythroid do not require accessory cells, but do require direct interaction with insulin-like growth factor I and/or insulin for erythroid development.

The presence of heterogeneous erythroid progenitor cells, contaminant cells, or serum may alter erythroid colony development in vitro. To obtain highly purified colony-forming units-erythroid (CFU-E), we cultured partially purified human blood burst-forming units-erythroid (BFU-E) in methylcellulose...

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Detalles Bibliográficos
Publicado en:J Clin Invest
Autores principales: Sawada, K, Krantz, S B, Dessypris, E N, Koury, S T, Sawyer, S T
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 1989
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC303879/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2651478/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114070
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