Lack of the endosomal SNAREs vti1a and vti1b led to significant impairments in neuronal development

Fusion between membranes is mediated by specific SNARE complexes. Here we report that fibroblasts survive the absence of the trans-Golgi network/early endosomal SNARE vti1a and the late endosomal SNARE vti1b with intact organelle morphology and minor trafficking defects. Because vti1a and vti1b are...

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Detalhes bibliográficos
Main Authors: Kunwar, Ajaya J., Rickmann, Michael, Backofen, Bianca, Browski, Sascha M., Rosenbusch, Joachim, Schöning, Susanne, Fleischmann, Thomas, Krieglstein, Kerstin, Fischer von Mollard, Gabriele
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3038762/
https://ncbi.nlm.nih.gov/pubmed/21262811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1013891108
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