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Rack1 is required for Vangl2 membrane localization and planar cell polarity signaling while attenuating canonical Wnt activity

The vertebrate planar cell polarity (PCP) pathway shares molecular components with the β-catenin–mediated canonical Wnt pathway but acts through membrane complexes containing Vang or Frizzled to orient neighboring cells coordinately. The molecular interactions underlying the action of Vang in PCP si...

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Hlavní autoři: Li, Shuangding, Esterberg, Robert, Lachance, Veronik, Ren, Dongdong, Radde-Gallwitz, Kristen, Chi, Fanglu, Parent, Jean-Luc, Fritz, Andreas, Chen, Ping
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3038753/
https://ncbi.nlm.nih.gov/pubmed/21262816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1013170108
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