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Rack1 is required for Vangl2 membrane localization and planar cell polarity signaling while attenuating canonical Wnt activity
The vertebrate planar cell polarity (PCP) pathway shares molecular components with the β-catenin–mediated canonical Wnt pathway but acts through membrane complexes containing Vang or Frizzled to orient neighboring cells coordinately. The molecular interactions underlying the action of Vang in PCP si...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3038753/ https://ncbi.nlm.nih.gov/pubmed/21262816 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1013170108 |
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