Protein kinase C is activated in glomeruli from streptozotocin diabetic rats. Possible mediation by glucose.

Glomerular inositol content and the turnover of polyphosphoinositides was reduced by 58% in 1-2 wk streptozotocin diabetic rats. Addition of inositol to the incubation medium increased polyphosphoinositide turnover in glomeruli from diabetic rats to control values. Despite the reduction in inositol...

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Publié dans:	J Clin Invest
Auteurs principaux:	Craven, P A, DeRubertis, F R
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Clinical Investigation 1989
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC303875/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2708528/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114066
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