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Processing mechanism and substrate selectivity of the core NuA4 histone acetyltransferase complex

Esa1, an essential MYST histone acetyltransferase found in the yeast piccolo NuA4 complex (picNuA4), is responsible for genome-wide histone H4 and histone H2A acetylation. picNuA4 uniquely catalyzes the rapid tetra-acetylation of nucleosomal H4, though the molecular determinants driving picNuA4 effi...

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Autori principali: Arnold, Kevin M., Lee, Susan, Denu, John M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3038686/
https://ncbi.nlm.nih.gov/pubmed/21182309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi101355a
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