Infusion of tumor necrosis factor/cachectin promotes muscle catabolism in the rat. A synergistic effect with interleukin 1.

To improve our understanding of the metabolic role of cytokines in protein wasting, we estimated the rates of protein synthesis and degradation in muscle and liver tissues in intact rats treated with several doses of recombinant IL 1 and/or tumor necrosis factor (TNF)/cachectin. Protein breakdown in...

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Detalhes bibliográficos
Main Authors: Flores, E A, Bistrian, B R, Pomposelli, J J, Dinarello, C A, Blackburn, G L, Istfan, N W
Formato: Artigo
Idioma:Inglês
Publicado em: 1989
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC303868/
https://ncbi.nlm.nih.gov/pubmed/2785120
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