Physical and Functional Interaction Between Calcineurin and the Cardiac L-Type Ca(2+) Channel

The L-type Ca(2+) channel (LTCC) is the major mediator of Ca(2+) influx in cardiomyocytes, leading to both mechanical contraction and activation of signaling cascades. Among these Ca(2+)-activated cascades is calcineurin, a protein phosphatase that promotes hypertrophic growth of the heart. Coimmuno...

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Main Authors: Tandan, Samvit, Wang, Yanggan, Wang, Thomas T., Jiang, Nan, Hall, Duane D., Hell, Johannes W., Luo, Xiang, Rothermel, Beverly A., Hill, Joseph A.
Format: Artigo
Jezik:Inglês
Izdano: 2009
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3038593/
https://ncbi.nlm.nih.gov/pubmed/19478199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.109.199828
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