Physical and Functional Interaction Between Calcineurin and the Cardiac L-Type Ca(2+) Channel

The L-type Ca(2+) channel (LTCC) is the major mediator of Ca(2+) influx in cardiomyocytes, leading to both mechanical contraction and activation of signaling cascades. Among these Ca(2+)-activated cascades is calcineurin, a protein phosphatase that promotes hypertrophic growth of the heart. Coimmuno...

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Bibliographic Details
Main Authors:	Tandan, Samvit, Wang, Yanggan, Wang, Thomas T., Jiang, Nan, Hall, Duane D., Hell, Johannes W., Luo, Xiang, Rothermel, Beverly A., Hill, Joseph A.
Format:	Artigo
Language:	Inglês
Published:	2009
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3038593/ https://ncbi.nlm.nih.gov/pubmed/19478199 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.109.199828
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Physical and Functional Interaction Between Calcineurin and the Cardiac L-Type Ca(2+) Channel

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