Dipeptidylpeptidase IV and trypsin-like enzymatic degradation of human growth hormone-releasing hormone in plasma.

The plasma enzyme responsible for primary proteolytic cleavage of growth hormone-releasing hormone (GRH) at the 2-3 amino acid bond was characterized. Native GRH[GRH(1-44)-NH2 and GRH(1-40)-OH], and COOH-terminally shortened fragments [GRH(1-32)-NH2 and GRH(1-29)-NH2] were rapidly cleaved, while GRH...

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Номзүйн дэлгэрэнгүй

-д хэвлэсэн:	J Clin Invest
Үндсэн зохиолчид:	Frohman, L A, Downs, T R, Heimer, E P, Felix, A M
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	American Society for Clinical Investigation 1989
Нөхцлүүд:	Research Article
Онлайн хандалт:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC303858/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2565342/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114049
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