TNF-α Antagonism with Etanercept Decreases Glucose and Increases the Proportion of High Molecular Weight Adiponectin in Obese Subjects with Features of the Metabolic Syndrome

Context and Objective: Obesity is associated with activation of the TNF-α system, increased inflammatory markers, and insulin resistance. Although studies in rodents suggest that attenuation of TNF activity improves glucose homeostasis, the effect of prolonged inhibition of TNF-α with etanercept on...

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Autores principales: Stanley, Takara L., Zanni, Markella V., Johnsen, Stine, Rasheed, Sarah, Makimura, Hideo, Lee, Hang, Khor, Victor K., Ahima, Rexford S., Grinspoon, Steven K.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Endocrine Society 2011
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3038481/
https://ncbi.nlm.nih.gov/pubmed/21047923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2010-1170
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