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Basal α-Cell Up-Regulation in Obese Insulin-Resistant Adolescents

Context: The aim of this analysis was to evaluate glucagon and c-peptide concentrations in two scenarios: euglycemic hyperinsulinemia and hyperglycemic hyperinsulinemia. We postulated that worsening obesity and insulin resistance will be reflected as an up-regulated (less suppressible) islet secreti...

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Detalhes bibliográficos
Main Authors: Weiss, Ram, D'Adamo, Ebe, Santoro, Nicola, Hershkop, Karen, Caprio, Sonia
Formato: Artigo
Idioma:Inglês
Publicado em: The Endocrine Society 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3038472/
https://ncbi.nlm.nih.gov/pubmed/20843946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2010-1275
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