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Increased polyamines may downregulate interleukin 2 production in rheumatoid arthritis.

Polyamines downregulate immune reactivity. RA is associated with decreased IL 2 production. In this study, we present evidence to suggest that excessive polyamines can contribute to the IL 2 deficiency in RA. Blocking polyamine production with inhibitors of ornithine decarboxylase results in increas...

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Detalhes bibliográficos
Main Authors: Flescher, E, Bowlin, T L, Ballester, A, Houk, R, Talal, N
Formato: Artigo
Idioma:Inglês
Publicado em: 1989
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC303829/
https://ncbi.nlm.nih.gov/pubmed/2784801
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