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Acute NADPH oxidase activation potentiates cerebrovascular permeability response to bradykinin in ischemia–reperfusion

Free radical generation is a key event in cerebral reperfusion injury. Bradykinin (Bk) and interleukin-1β (IL-1β) have both been implicated in edema formation after stroke, although acute Bk application itself results in only a modest permeability increase. We have investigated the molecular mechani...

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Hlavní autoři: Woodfin, Abigail, Hu, De-En, Sarker, Mosharraf, Kurokawa, Tsuyoshi, Fraser, Paul
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier Science 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3038265/
https://ncbi.nlm.nih.gov/pubmed/21167936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2010.12.010
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