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CD11c/CD18 expression is upregulated on blood monocytes during hypertriglyceridemia and enhances adhesion to VCAM-1

OBJECTIVE: Atherosclerosis is associated with monocyte adhesion to the arterial wall that involves integrin activation and emigration across inflamed endothelium. Involvement of β2-integrin CD11c/CD18 in atherogenesis was recently shown in dyslipidemic mice, which motivates our study of its inflamma...

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Detalhes bibliográficos
Main Authors: Gower, R. Michael, Wu, Huaizhu, Foster, Greg A., Devaraj, Sridevi, Jialal, Ishwarlal, Ballantyne, Christie M., Knowlton, Anne A., Simon, Scott I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3038249/
https://ncbi.nlm.nih.gov/pubmed/21030716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.110.215434
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