Rearrangement of variable region T cell receptor gamma genes in acute lymphoblastic leukemia. V gamma gene usage differs in mature and immature T cells.

Using probes recognizing variable regions (V gamma) and joining regions (J gamma) of the T cell receptor (TCR) gamma gene, we have analyzed the usage of V gamma genes in 24 patients with T cell acute lymphoblastic leukemia (ALL) and 36 patients with B-precursor ALL. In CD3- T-ALL derived from immatu...

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Bibliographic Details
Published in:J Clin Invest
Main Authors: Hara, J, Benedict, S H, Yumura, K, Ha-Kawa, K, Gelfand, E W
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 1989
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC303818/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2522937/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114012
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