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On the role of v-ATPase V0a1-dependent degradation in Alzheimer disease
Defective autophagy and lysosomal degradation are hallmarks of numerous neurodegenerative disorders. Vesicular ATPases are intracellular proton pumps that acidify autophagosomes and lysosomes. V0a1 is a key component of the v-ATPase that is only required in neurons in Drosophila melanogaster. We hav...
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| Hlavní autoři: | , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Landes Bioscience
2010
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3038078/ https://ncbi.nlm.nih.gov/pubmed/21331254 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cib.3.6.13364 |
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