Loading...

On the role of v-ATPase V0a1-dependent degradation in Alzheimer disease

Defective autophagy and lysosomal degradation are hallmarks of numerous neurodegenerative disorders. Vesicular ATPases are intracellular proton pumps that acidify autophagosomes and lysosomes. V0a1 is a key component of the v-ATPase that is only required in neurons in Drosophila melanogaster. We hav...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Williamson, W Ryan, Hiesinger, P Robin
Format: Artigo
Sprog:Inglês
Udgivet: Landes Bioscience 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3038078/
https://ncbi.nlm.nih.gov/pubmed/21331254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cib.3.6.13364
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!