Llwytho...

On the role of v-ATPase V0a1-dependent degradation in Alzheimer disease

Defective autophagy and lysosomal degradation are hallmarks of numerous neurodegenerative disorders. Vesicular ATPases are intracellular proton pumps that acidify autophagosomes and lysosomes. V0a1 is a key component of the v-ATPase that is only required in neurons in Drosophila melanogaster. We hav...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Williamson, W Ryan, Hiesinger, P Robin
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Landes Bioscience 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3038078/
https://ncbi.nlm.nih.gov/pubmed/21331254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cib.3.6.13364
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