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Post-transcriptional regulation of amyloid precursor protein by microRNAs and RNA binding proteins
Amyloid Precursor Protein (APP) and its proteolytic product amyloid beta (Aβ) are critical in the pathogenesis of Alzheimer's Disease (AD). APP gene duplication and transcriptional upregulation are linked to AD. In addition, normal levels of APP appear to be required for some physiological func...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3038048/ https://ncbi.nlm.nih.gov/pubmed/21331224 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cib.3.6.13172 |
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