RNA Binding Protein CUGBP2/CELF2 Mediates Curcumin-Induced Mitotic Catastrophe of Pancreatic Cancer Cells

BACKGROUND: Curcumin inhibits the growth of pancreatic cancer tumor xenografts in nude mice; however, the mechanism of action is not well understood. It is becoming increasingly clear that RNA binding proteins regulate posttranscriptional gene expression and play a critical role in RNA stability and...

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Detalhes bibliográficos
Main Authors: Subramaniam, Dharmalingam, Ramalingam, Satish, Linehan, David C., Dieckgraefe, Brian K., Postier, Russell G., Houchen, Courtney W., Jensen, Roy A., Anant, Shrikant
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3037932/
https://ncbi.nlm.nih.gov/pubmed/21347286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016958
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